Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	730822
Species:	Mus musculus
RGD Object:	Gene
Symbol:	Mmp2
Name:	matrix metallopeptidase 2

Acc ID:	CHEBI:15920
Term:	columbamine
Definition:	A berberine alkaloid that has formula C20H20NO4.
Chemical ID:	MESH:C055786

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Mmp2	decreases expression	ISO	MMP2 (Homo sapiens)	6480464	CTD	columbamine results in decreased expression of MMP2 mRNA	PMID:23124089

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.