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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1350497
Species: Homo sapiens
RGD Object: Gene
Symbol: NDUFA1
Name: NADH:ubiquinone oxidoreductase subunit A1
Acc ID: CHEBI:15891
Term: taurine
Definition: An amino sulfonic acid that is the 2-amino derivative of ethanesulfonic acid. It is a naturally occurring amino acid derived from methionine and cysteine metabolism. An abundant component of fish- and meat-based foods, it has been used as an oral supplement in the treatment of disorders such as cystic fibrosis and hypertension.
Chemical ID: MESH:D013654
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NDUFA1multiple interactionsEXP 6480464CTD[Taurine co-treated with 3-methyladenine] inhibits the reaction [1-nitropyrene results in decreased expression of NDUFA1 mRNA]PMID:29078374
NDUFA1multiple interactionsISONdufa1 (Mus musculus)6480464CTD[3-methyladenine co-treated with Taurine] inhibits the reaction [1-nitropyrene results in decreased expression of NDUFA1 mRNA]PMID:29078374
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