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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2890
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1a
Name: interleukin 1 alpha
Acc ID: CHEBI:15882
Term: phenol
Definition: An organic hydroxy compound that consists of benzene bearing a single hydroxy substituent. The parent of the class of phenols.
Chemical ID: MESH:D019800
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1aincreases expressionISOIL1A (Homo sapiens)6480464CTDPhenol results in increased expression of IL1A mRNA; Phenol results in increased expression of IL1A proteinPMID:8006454
Il1aincreases secretionISOIL1A (Homo sapiens)6480464CTDPhenol results in increased secretion of IL1A proteinPMID:16522979
Il1amultiple interactionsISOIL1A (Homo sapiens)6480464CTDIL1A protein affects the reaction [Phenol results in increased expression of CXCL8 protein]PMID:8006454
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