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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3706
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc2a3
Name: solute carrier family 2 member 3
Acc ID: CHEBI:15866
Term: 2-deoxy-D-glucose
Definition: A deoxyglucose that is D-glucose in which the hydroxy group at position 2 has been replaced by a hydrogen. It is an antimetabolite of glucose with antiviral activity, which acts by inhibiting the glycosylation of glycoproteins and glycolipids. Used as an antiherpes agent.
Chemical ID: MESH:D003847
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc2a3increases transportISORGD:7370556480464CTDSLC2A3 protein results in increased transport of Deoxyglucose

PMID:8457197
Slc2a3multiple interactionsISORGD:7370556480464CTDCytochalasin B inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose] Galactose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose] Glucose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose] Maltose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]

PMID:8457197
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