Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2173
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fxyd2
Name: FXYD domain-containing ion transport regulator 2
Acc ID: CHEBI:15866
Term: 2-deoxy-D-glucose
Definition: A deoxyglucose that is D-glucose in which the hydroxy group at position 2 has been replaced by a hydrogen. It is an antimetabolite of glucose with antiviral activity, which acts by inhibiting the glycosylation of glycoproteins and glycolipids. Used as an antiherpes agent.
Chemical ID: MESH:D003847
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fxyd2increases transportISORGD:13426696480464CTDFXYD2 protein results in increased transport of DeoxyglucosePMID:11533133
Fxyd2multiple interactionsISORGD:13426696480464CTDCalcium inhibits the reaction [FXYD2 protein results in increased transport of Deoxyglucose]PMID:11533133
Go Back to source page   Continue to Ontology report