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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310482
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsp90b1
Name: heat shock protein 90 beta family member 1
Acc ID: CHEBI:15866
Term: 2-deoxy-D-glucose
Definition: A deoxyglucose that is D-glucose in which the hydroxy group at position 2 has been replaced by a hydrogen. It is an antimetabolite of glucose with antiviral activity, which acts by inhibiting the glycosylation of glycoproteins and glycolipids. Used as an antiherpes agent.
Chemical ID: MESH:D003847
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsp90b1increases expressionISORGD:13214096480464CTDDeoxyglucose results in increased expression of HSP90B1 protein

PMID:31022492
Hsp90b1multiple interactionsISORGD:13214096480464CTD4-Quinolones analog inhibits the reaction [Deoxyglucose results in increased expression of HSP90B1 protein]

PMID:31022492
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