GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Slc22a1 | multiple interactions | EXP | | 6480464 | CTD | Quinine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] | PMID:16142924 | Slc22a1 | decreases activity | ISO | SLC22A1 (Homo sapiens) | 6480464 | CTD | Quinine results in decreased activity of SLC22A1; Quinine results in decreased activity of SLC22A1 protein | PMID:25844889 PMID:31830554 | Slc22a1 | increases uptake | ISO | SLC22A1 (Homo sapiens) | 6480464 | CTD | SLC22A1 protein results in increased uptake of Quinine | PMID:27504015 | Slc22a1 | multiple interactions | ISO | SLC22A1 (Homo sapiens) | 6480464 | CTD | [Quinine results in decreased activity of SLC22A1] which results in decreased uptake of abacavir; Quinine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Quinine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; Quinine inhibits the reaction [SLC22A1 protein results in increased uptake of Ethidium] | PMID:16263091 PMID:19357179 PMID:25844889 PMID:27504015 | | ||||||||||||||||||||||
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