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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69231
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd17b10
Name: hydroxysteroid (17-beta) dehydrogenase 10
Acc ID: CHEBI:15846
Term: NAD(+)
Definition: The oxidised form of nicotinamide adenine dinucleotide found in all living cells. In metabolism, NAD(+) is involved in redox reactions, carrying electrons from one reaction to another.
Chemical ID: MESH:D009243
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd17b10multiple interactionsISOHSD17B10 (Homo sapiens)6480464CTD[20-hydroxycholesterol co-treated with NAD] binds to HSD17B10 protein; [Androstane-3,17-diol co-treated with NAD] binds to HSD17B10 protein; [cholest-5-en-3 beta,7 alpha-diol co-treated with NAD] binds to HSD17B10 protein; [Cholestanol co-treated with NAD] binds to HSD17B10 protein; [Pregnanolone co-treated with NAD] binds to HSD17B10 protein; [Progesterone co-treated with NAD] binds to HSD17B10 protein; NAD binds to and results in increased activity of HSD17B10 proteinPMID:25526675
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