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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734103
Species: Homo sapiens
RGD Object: Gene
Symbol: NR1H4
Name: nuclear receptor subfamily 1 group H member 4
Acc ID: CHEBI:15843
Term: arachidonic acid
Definition: A long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14.
Chemical ID: MESH:D016718
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NR1H4affects bindingEXP 6480464CTDArachidonic Acid binds to NR1H4 proteinPMID:15307955
NR1H4multiple interactionsEXP 6480464CTDArachidonic Acid inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]PMID:15307955
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