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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732638
Species: Mus musculus
RGD Object: Gene
Symbol: Ppara
Name: peroxisome proliferator activated receptor alpha
Acc ID: CHEBI:15843
Term: arachidonic acid
Definition: A long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14.
Chemical ID: MESH:D016718
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pparaincreases expressionISOPPARA (Homo sapiens)6480464CTDArachidonic Acid results in increased expression of PPARA mRNA; Arachidonic Acid results in increased expression of PPARA proteinPMID:11172467
Pparamultiple interactionsISOPPARA (Homo sapiens)6480464CTDArachidonic Acid binds to and results in increased activity of PPARA proteinPMID:10403814 PMID:15491415
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