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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68353
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr5a2
Name: nuclear receptor subfamily 5, group A, member 2
Acc ID: CHEBI:15843
Term: arachidonic acid
Definition: A long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14.
Chemical ID: MESH:D016718
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr5a2decreases chemical synthesisISONr5a2 (Mus musculus)6480464CTDNR5A2 gene mutant form results in decreased chemical synthesis of Arachidonic AcidPMID:29515023
Nr5a2multiple interactionsISONr5a2 (Mus musculus)6480464CTD[NR5A2 gene mutant form results in increased susceptibility to Dietary Fats] which results in decreased abundance of Arachidonic Acid analogPMID:29515023
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