GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | increases activity | ISO | Casp3 (Mus musculus) | 6480464 | CTD | Arachidonic Acid results in increased activity of CASP3 protein | PMID:23266427 | Casp3 | increases activity | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Arachidonic Acid results in increased activity of CASP3 protein | PMID:16704987 PMID:19720122 | Casp3 | increases degradation | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Arachidonic Acid results in increased degradation of CASP3 protein alternative form | PMID:19540902 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in increased degradation of CASP3 protein alternative form]; [Arachidonic Acid co-treated with Iron] results in decreased expression of CASP3 protein; [Arachidonic Acid co-treated with Iron] results in increased cleavage of CASP3 protein; [Arachidonic Acid co-treated with Iron] results in increased expression of CASP3 protein modified form; Drugs, Chinese Herbal inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased cleavage of CASP3 protein]; FADD protein promotes the reaction [Arachidonic Acid results in increased activity of CASP3 protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased cleavage of CASP3 protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of CASP3 protein modified form]; Resveratrol inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in decreased expression of CASP3 protein] | PMID:19540902 PMID:19620254 PMID:19720122 PMID:27916511 PMID:30626086 | | ||||||||||||||||||||||
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