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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3959
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vdr
Name: vitamin D receptor
Acc ID: CHEBI:1582
Term: 3-methoxytyramine
Definition: A monomethoxybenzene that is dopamine in which the hydroxy group at position 3 is replaced by a methoxy group. It is a metabolite of the neurotransmitter dopamine and considered a potential biomarker of pheochromocytomas and paragangliomas.
Chemical ID: MESH:C001746
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vdrincreases abundanceISOVDR (Homo sapiens)6480464CTDVDR protein results in increased abundance of 3-methoxytyraminePMID:27450565
Vdrmultiple interactionsISOVDR (Homo sapiens)6480464CTDCalcitriol promotes the reaction [VDR protein results in increased abundance of 3-methoxytyramine]PMID:27450565
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