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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311629
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dapk1
Name: death associated protein kinase 1
Acc ID: CHEBI:15767
Term: dichloromethane
Definition: A member of the class of chloromethanes that is methane in which two of the hydrogens have been replaced by chlorine. A dense, non-flammible colourless liquid at room temperature (b.p. 40degreeC, d = 1.33) which is immiscible with water, it is widely used as a solvent, a paint stripper, and for the removal of caffeine from coffee and tea.
Chemical ID: MESH:D008752
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases methylationISORGD:13231866480464CTDMethylene Chloride results in increased methylation of DAPK1 promoter

PMID:15172992
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.