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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733604
Species: Mus musculus
RGD Object: Gene
Symbol: Apoe
Name: apolipoprotein E
Acc ID: CHEBI:15756
Term: hexadecanoic acid
Definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Chemical ID: MESH:D019308
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apoedecreases expressionEXP 6480464CTDPalmitic Acid results in decreased expression of APOE mRNA; Palmitic Acid results in decreased expression of APOE proteinPMID:34485530
Apoemultiple interactionsEXP 6480464CTDmorroniside inhibits the reaction [Palmitic Acid results in decreased expression of APOE mRNA]; morroniside inhibits the reaction [Palmitic Acid results in decreased expression of APOE protein]PMID:34485530
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