GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk8 | increases phosphorylation | EXP | | 6480464 | CTD | Palmitic Acid results in increased phosphorylation of MAPK8 protein | PMID:21134603 PMID:34678374 | Mapk8 | multiple interactions | EXP | | 6480464 | CTD | carnosol inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]; Chromium inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]] | PMID:21134603 PMID:34678374 | Mapk8 | increases expression | ISO | Mapk8 (Rattus norvegicus) | 6480464 | CTD | Palmitic Acid results in increased expression of MAPK8 mRNA | PMID:30259999 | Mapk8 | increases phosphorylation | ISO | Mapk8 (Rattus norvegicus) | 6480464 | CTD | Palmitic Acid results in increased phosphorylation of MAPK8 protein | PMID:34979142 | Mapk8 | increases phosphorylation | ISO | MAPK8 (Homo sapiens) | 6480464 | CTD | Palmitic Acid results in increased phosphorylation of MAPK8 protein | PMID:21745629 | Mapk8 | multiple interactions | ISO | Mapk8 (Rattus norvegicus) | 6480464 | CTD | 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK8 protein]]; 7-hydroxycoumarin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of and results in increased phosphorylation of MAPK8 protein]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Palmitic Acid results in increased expression of and results in increased phosphorylation of MAPK8 protein; parthenolide inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]; Scopoletin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein] | PMID:25109277 PMID:30259999 PMID:34979142 | Mapk8 | multiple interactions | ISO | MAPK8 (Homo sapiens) | 6480464 | CTD | Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein] | PMID:21745629 | | ||||||||||||||||||||||
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