Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731946
Species: Mus musculus
RGD Object: Gene
Symbol: Ppard
Name: peroxisome proliferator activator receptor delta
Acc ID: CHEBI:15756
Term: hexadecanoic acid
Definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Chemical ID: MESH:D019308
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppardmultiple interactionsISOPpard (Rattus norvegicus)6480464CTD[Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of PPARD mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARB mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARD mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARB mRNA]; tetrabromobisphenol A inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARD mRNA]PMID:25048947 PMID:26190035 PMID:26854922
Ppardmultiple interactionsISOPPARD (Homo sapiens)6480464CTD[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of PPARD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PPARD mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PPARD mRNAPMID:30547786 PMID:32613381
Go Back to source page   Continue to Ontology report