GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ddit3 | increases expression | EXP | | 6480464 | CTD | Palmitic Acid results in increased expression of DDIT3 mRNA | PMID:34979142 | Ddit3 | multiple interactions | EXP | | 6480464 | CTD | Scopoletin inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 mRNA] | PMID:34979142 | Ddit3 | increases expression | ISO | Ddit3 (Mus musculus) | 6480464 | CTD | Palmitic Acid results in increased expression of DDIT3 mRNA; Palmitic Acid results in increased expression of DDIT3 protein | PMID:29414781 PMID:30208301 PMID:36030031 | Ddit3 | increases expression | ISO | DDIT3 (Homo sapiens) | 6480464 | CTD | Palmitic Acid results in increased expression of DDIT3 mRNA | PMID:30738135 | Ddit3 | multiple interactions | ISO | Ddit3 (Mus musculus) | 6480464 | CTD | 4-phenylbutyric acid promotes the reaction [Palmitic Acid results in increased expression of DDIT3 mRNA]; 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 protein]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; GSK2656157 inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 mRNA]; GSK2656157 inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 protein]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 protein]] | PMID:29414781 PMID:36030031 PMID:37009739 | Ddit3 | multiple interactions | ISO | DDIT3 (Homo sapiens) | 6480464 | CTD | 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of DDIT3 mRNA]; [Palmitic Acid co-treated with Arsenic] results in increased expression of DDIT3 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of DDIT3 mRNA; Ivermectin promotes the reaction [Palmitic Acid results in increased expression of DDIT3 protein]; Permethrin inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 mRNA] | PMID:30738135 PMID:32369900 PMID:33736254 | | ||||||||||||||||||||||
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