Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620283
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Foxo1
Name: forkhead box O1
Acc ID: CHEBI:15756
Term: hexadecanoic acid
Definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Chemical ID: MESH:D019308
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases phosphorylationEXP 6480464CTDPalmitic Acid results in decreased phosphorylation of FOXO1 protein

PMID:22819839
increases localizationEXP 6480464CTDPalmitic Acid results in increased localization of FOXO1 protein

PMID:22968147
multiple interactionsEXP 6480464CTDgeniposide inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein], resveratrol inhibits the reaction [Palmitic Acid results in increased localization of FOXO1 protein]

PMID:22819839, PMID:22968147
decreases phosphorylationISORGD:7371566480464CTDPalmitic Acid results in decreased phosphorylation of FOXO1 protein

PMID:21255808
multiple interactionsISORGD:7371566480464CTD[GCG protein co-treated with candesartan] inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein], candesartan inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein], GCG protein inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]

PMID:21255808
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.