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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1351472
Species: Homo sapiens
RGD Object: Gene
Symbol: ADIPOQ
Name: adiponectin, C1Q and collagen domain containing
Acc ID: CHEBI:15756
Term: hexadecanoic acid
Definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Chemical ID: MESH:D019308
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ADIPOQmultiple interactionsEXP 6480464CTD[osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOQ mRNA; [osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOQ protein; MRI-1867 inhibits the reaction [[osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOQ mRNA]; MRI-1867 inhibits the reaction [[osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOQ protein]PMID:31454063
ADIPOQdecreases expressionISOAdipoq (Rattus norvegicus)6480464CTDPalmitic Acid results in decreased expression of ADIPOQ mRNAPMID:25108154
ADIPOQincreases expressionISOAdipoq (Mus musculus)6480464CTDPalmitic Acid results in increased expression of ADIPOQ proteinPMID:34968464
ADIPOQmultiple interactionsISOAdipoq (Mus musculus)6480464CTD[Palmitic Acid co-treated with sodium arsenite] results in decreased expression of ADIPOQ mRNA; [Palmitic Acid co-treated with sodium arsenite] results in decreased expression of and results in decreased secretion of ADIPOQ protein; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of ADIPOQ mRNA; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of ADIPOQ protein; Palmitic Acid inhibits the reaction [[sodium arsenite co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased secretion of ADIPOQ protein]; sodium arsenite inhibits the reaction [Palmitic Acid results in increased expression of ADIPOQ protein]PMID:34968464
ADIPOQmultiple interactionsISOAdipoq (Rattus norvegicus)6480464CTDAICA ribonucleotide inhibits the reaction [Palmitic Acid results in decreased expression of ADIPOQ mRNA]; Metformin inhibits the reaction [Palmitic Acid results in decreased expression of ADIPOQ mRNA]; resveratrol inhibits the reaction [Palmitic Acid results in decreased expression of ADIPOQ mRNA]; Salicylic Acid inhibits the reaction [Palmitic Acid results in decreased expression of ADIPOQ mRNA]PMID:25108154
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