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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11481
Species: Mus musculus
RGD Object: Gene
Symbol: Vcam1
Name: vascular cell adhesion molecule 1
Acc ID: CHEBI:15756
Term: hexadecanoic acid
Definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Chemical ID: MESH:D019308
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vcam1increases expressionISOVCAM1 (Homo sapiens)6480464CTDPalmitic Acid results in increased expression of VCAM1 mRNA; Palmitic Acid results in increased expression of VCAM1 proteinPMID:26422990 PMID:27107694
Vcam1multiple interactionsISOVCAM1 (Homo sapiens)6480464CTDcyanidin-3-O-beta-glucopyranoside inhibits the reaction [Palmitic Acid results in increased expression of VCAM1 mRNA]; geraniol inhibits the reaction [Palmitic Acid results in increased expression of VCAM1 protein]; wedelolactone inhibits the reaction [Palmitic Acid results in increased expression of VCAM1 mRNA]PMID:26422990 PMID:27107694
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