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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10717
Species: Mus musculus
RGD Object: Gene
Symbol: Hmox1
Name: heme oxygenase 1
Acc ID: CHEBI:15756
Term: hexadecanoic acid
Definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Chemical ID: MESH:D019308
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmox1multiple interactionsEXP 6480464CTD[amlexanox co-treated with Palmitic Acid] results in increased expression of HMOX1 mRNAPMID:32905826
Hmox1increases expressionISOHmox1 (Rattus norvegicus)6480464CTDPalmitic Acid results in increased expression of HMOX1 mRNAPMID:28027979
Hmox1increases expressionISOHMOX1 (Homo sapiens)6480464CTDPalmitic Acid results in increased expression of HMOX1 proteinPMID:37117602
Hmox1multiple interactionsISOHMOX1 (Homo sapiens)6480464CTD[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein]; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein]PMID:32976958 PMID:36905866
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