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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730900
Species: Homo sapiens
RGD Object: Gene
Symbol: PPP3CA
Name: protein phosphatase 3 catalytic subunit alpha
Acc ID: CHEBI:15738
Term: staurosporine
Definition: An indolocarbazole alkaloid that has formula C28H26N4O3.
Chemical ID: MESH:D019311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PPP3CAincreases cleavageEXP 6480464CTDStaurosporine results in increased cleavage of PPP3CA proteinPMID:10898953
PPP3CAdecreases response to substanceISOPpp3ca (Mus musculus)6480464CTDPPP3CA protein results in decreased susceptibility to StaurosporinePMID:10679475
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