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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733483
Species: Homo sapiens
RGD Object: Gene
Symbol: MTHFR
Name: methylenetetrahydrofolate reductase
Acc ID: CHEBI:15640
Term: 5-formyltetrahydrofolic acid
Definition: A formyltetrahydrofolic acid in which the formyl group is located at position 5.
Chemical ID: MESH:D002955
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MTHFRmultiple interactionsEXP 6480464CTDMTHFR gene polymorphism results in increased susceptibility to [Fluorouracil co-treated with Leucovorin]PMID:18633250
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