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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551620
Species: Mus musculus
RGD Object: Gene
Symbol: Aldh1l2
Name: aldehyde dehydrogenase 1 family, member L2
Acc ID: CHEBI:15637
Term: 10-formyltetrahydrofolic acid
Definition: A form of tetrahydrofolate that acts as a donor of formyl groups in anabolism. In these reactions 10-formyltetrahydrofolic acid is used as a substrate in formyltransferase reactions, which is important in purine biosynthesis.
Chemical ID: MESH:C010161
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases metabolic processingISORGD:13456176480464CTDALDH1L2 protein results in increased metabolism of 10-formyltetrahydropteroylglutamic acid

PMID:21238436
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