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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733096
Species: Mus musculus
RGD Object: Gene
Symbol: Hmbs
Name: hydroxymethylbilane synthase
Acc ID: CHEBI:15633
Term: dihydrofolic acid
Definition: A folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid. It interacts with bacteria during cell division and is targeted by various drugs to prevent nucleic acid synthesis.
Chemical ID: MESH:C010920
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmbsincreases activityISOHmbs (Rattus norvegicus)26884337RGDDihydrofolic acid increases activity of purified Hmbs protein 
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