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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69251
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hpgds
Name: hematopoietic prostaglandin D synthase
Acc ID: CHEBI:15555
Term: prostaglandin D2
Definition: A member of the class of prostaglandins D that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9 and 15 and an oxo group at position 11 (the 5Z,9alpha,13E,15S- stereoisomer).
Chemical ID: MESH:D015230
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hpgdsmultiple interactionsISOHpgds (Mus musculus)6480464CTD[4-benzhydryloxy-1-(3-(1H-tetrazol-5-yl-)-propyl)piperidine results in increased expression of HPGDS mRNA] which results in decreased abundance of Prostaglandin D2PMID:21352547
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