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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732129
Species: Mus musculus
RGD Object: Gene
Symbol: Il11
Name: interleukin 11
Acc ID: CHEBI:15551
Term: prostaglandin E2
Definition: Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins.
Chemical ID: MESH:D015232
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il11increases abundanceEXP 6480464CTDIL11 protein results in increased abundance of DinoprostonePMID:12110441
Il11multiple interactionsEXP 6480464CTDFlurbiprofen inhibits the reaction [IL11 protein results in increased abundance of Dinoprostone]; Indomethacin inhibits the reaction [IL11 protein results in increased abundance of Dinoprostone]PMID:12110441
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