GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nos2 | multiple interactions | EXP | | 6480464 | CTD | Dinoprostone inhibits the reaction [Indomethacin results in increased activity of NOS2 protein]; Dinoprostone inhibits the reaction [Indomethacin results in increased expression of NOS2 mRNA] | PMID:16944022 | Nos2 | increases response to substance | ISO | Nos2 (Mus musculus) | 6480464 | CTD | NOS2 results in increased susceptibility to Dinoprostone | PMID:15491851 | Nos2 | multiple interactions | ISO | Nos2 (Mus musculus) | 6480464 | CTD | [Ozone results in increased expression of NOS2 protein] which results in increased abundance of Dinoprostone; Dinoprostone inhibits the reaction [PTGS1 gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]]; NOS2 protein promotes the reaction [[Morphine results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone] | PMID:11919077 PMID:16325209 PMID:25432964 | Nos2 | multiple interactions | ISO | NOS2 (Homo sapiens) | 6480464 | CTD | [Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased chemical synthesis of Dinoprostone; honokiol inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased chemical synthesis of Dinoprostone] | PMID:21147091 | | ||||||||||||||||||||||
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