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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1595785
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rorc
Name: RAR-related orphan receptor C
Acc ID: CHEBI:15551
Term: prostaglandin E2
Definition: Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins.
Chemical ID: MESH:D015232
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rorcincreases expressionISORORC (Homo sapiens)6480464CTDDinoprostone results in increased expression of RORCPMID:19273625
Rorcmultiple interactionsISORORC (Homo sapiens)6480464CTDDinoprostone promotes the reaction [[IL1B co-treated with IL23A] results in increased expression of RORC mRNA]PMID:19273625
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