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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551314
Species: Mus musculus
RGD Object: Gene
Symbol: Csf2
Name: colony stimulating factor 2 (granulocyte-macrophage)
Acc ID: CHEBI:15551
Term: prostaglandin E2
Definition: Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins.
Chemical ID: MESH:D015232
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Csf2multiple interactionsEXP 6480464CTDCSF2 protein promotes the reaction [Dinoprostone results in increased expression of [IL12B protein binds to IL23A protein]]PMID:15180965
Csf2multiple interactionsISOCSF2 (Homo sapiens)6480464CTD[IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Dinoprostone co-treated with IL1B protein co-treated with IL6 protein] results in increased expression of CCR7 protein; [IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Dinoprostone co-treated with IL1B protein co-treated with IL6 protein] results in increased expression of MUC1 proteinPMID:18952292
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