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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735822
Species: Mus musculus
RGD Object: Gene
Symbol: Ucp1
Name: uncoupling protein 1 (mitochondrial, proton carrier)
Acc ID: CHEBI:15422
Term: ATP
Definition: An adenosine 5'-phosphate in which the 5'-phosphate is a triphosphate group. It is involved in the transportation of chemical energy during metabolic pathways.
Chemical ID: MESH:D000255
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ucp1decreases abundanceEXP 6480464CTDUCP1 results in decreased abundance of Adenosine TriphosphatePMID:26670611
Ucp1multiple interactionsISOUcp1 (Rattus norvegicus)6480464CTDAdenosine Triphosphate inhibits the reaction [UCP1 protein results in increased transport of Protons]PMID:12734183
Ucp1multiple interactionsISOUCP1 (Homo sapiens)6480464CTDUCP1 protein promotes the reaction [PPARG protein mutant form results in decreased abundance of Adenosine Triphosphate]; UCP1 protein promotes the reaction [rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]]PMID:26670611
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