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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307993
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcr
Name: BCR activator of RhoGEF and GTPase
Acc ID: CHEBI:15422
Term: ATP
Definition: An adenosine 5'-phosphate in which the 5'-phosphate is a triphosphate group. It is involved in the transportation of chemical energy during metabolic pathways.
Chemical ID: MESH:D000255
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:13175066480464CTD[BCR protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein, sorafenib inhibits the reaction [[BCR protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein]

PMID:19366808
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.