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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735253
Species: Mus musculus
RGD Object: Gene
Symbol: Scn5a
Name: sodium channel, voltage-gated, type V, alpha
Acc ID: CHEBI:15384
Term: limonene
Definition: A monoterpene that is cyclohex-1-ene substituted by a methyl group at position 1 and a prop-1-en-2-yl group at position 4 respectively.
Chemical ID: MESH:C008281
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scn5amultiple interactionsISOSCN5A (Homo sapiens)6480464CTDlimonene inhibits the reaction [2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate results in increased activity of SCN5A protein]PMID:29306026
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