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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735622
Species: Mus musculus
RGD Object: Gene
Symbol: Gdf15
Name: growth differentiation factor 15
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gdf15increases expressionEXP 6480464CTDOxygen results in increased expression of GDF15PMID:28734801
Gdf15multiple interactionsEXP 6480464CTD[NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of GDF15 mRNAPMID:30529165
Gdf15decreases expressionISOGDF15 (Homo sapiens)6480464CTDOxygen deficiency results in decreased expression of GDF15 mRNAPMID:26516004
Gdf15increases expressionISOGDF15 (Homo sapiens)6480464CTDOxygen deficiency results in increased expression of GDF15 mRNA; Oxygen results in increased expression of GDF15 mRNA; Oxygen results in increased expression of GDF15 proteinPMID:25596134 PMID:28734801
Gdf15multiple interactionsISOGDF15 (Homo sapiens)6480464CTDOxygen deficiency inhibits the reaction [darinaparsin results in decreased expression of GDF15 mRNA]PMID:22535156
Gdf15multiple interactionsISOGdf15 (Rattus norvegicus)6480464CTD[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of GDF15 mRNAPMID:33729688
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