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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733858
Species: Homo sapiens
RGD Object: Gene
Symbol: IREB2
Name: iron responsive element binding protein 2
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IREB2decreases expressionEXP 6480464CTDOxygen deficiency results in decreased expression of IREB2 mRNA; Oxygen deficiency results in decreased expression of IREB2 proteinPMID:33969609
IREB2multiple interactionsISOIreb2 (Rattus norvegicus)6480464CTD[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of IREB2 protein; Deferoxamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of IREB2 protein]PMID:16135072
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