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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733275
Species: Homo sapiens
RGD Object: Gene
Symbol: TFRC
Name: transferrin receptor
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TFRCdecreases expressionEXP 6480464CTDOxygen deficiency results in decreased expression of TFRC mRNA; Oxygen deficiency results in decreased expression of TFRC proteinPMID:33969609
TFRCincreases expressionEXP 6480464CTDOxygen deficiency results in increased expression of TFRC mRNAPMID:19502547
TFRCmultiple interactionsEXP 6480464CTD[cobaltous chloride results in decreased abundance of Oxygen] which results in increased expression of TFRC protein; [Deferoxamine results in decreased abundance of Oxygen] which results in increased expression of TFRC proteinPMID:17442736
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