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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733128
Species: Homo sapiens
RGD Object: Gene
Symbol: VIM
Name: vimentin
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
VIMincreases expressionEXP 6480464CTDOxygen deficiency results in increased expression of VIM mRNA; Oxygen deficiency results in increased expression of VIM proteinPMID:25351418
VIMmultiple interactionsEXP 6480464CTD[dictamnine co-treated with Oxygen deficiency] results in decreased expression of VIM protein; [Oxygen deficiency co-treated with Oxygen] results in decreased expression of VIM protein; ALCAM protein inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of VIM protein]; ALKBH5 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of VIM protein]; PKF115-584 promotes the reaction [ALKBH5 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of VIM protein]]; PPARG protein inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of VIM protein]PMID:30266538 PMID:34995009
VIMincreases expressionISOVim (Rattus norvegicus)6480464CTDOxygen results in increased expression of VIM mRNAPMID:22911455
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