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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732178
Species: Homo sapiens
RGD Object: Gene
Symbol: AKR1B1
Name: aldo-keto reductase family 1 member B
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AKR1B1multiple interactionsISOAkr1b1 (Rattus norvegicus)6480464CTDAKR1B1 protein inhibits the reaction [Oxygen deficiency results in increased phosphorylation of EIF2A protein]; AKR1B1 protein inhibits the reaction [Oxygen deficiency results in increased phosphorylation of EIF2AK3 protein]PMID:19041636
AKR1B1multiple interactionsISOAkr1b1 (Mus musculus)6480464CTDAKR1B1 protein promotes the reaction [Oxygen deficiency results in increased expression of TNF protein]; AKR1B1 protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA protein]PMID:30682331
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