Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Oxygen deficiency results in increased expression of HMOX1 mRNA; Oxygen deficiency results in increased expression of HMOX1 protein; Oxygen results in increased expression of HMOX1 mRNA; Oxygen results in increased expression of HMOX1 protein
1,10-phenanthroline inhibits the reaction [Oxygen results in increased expression of HMOX1 mRNA]; 3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Oxygen deficiency results in increased expression of HMOX1 mRNA]; [Oxygen co-treated with Glucose] promotes the reaction [Vehicle Emissions promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 protein]]; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 protein; Acetylcysteine promotes the reaction [Oxygen results in increased expression of HMOX1 mRNA]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of HMOX1 mRNA]; Cycloheximide inhibits the reaction [Oxygen results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Oxygen results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Oxygen results in increased expression of HMOX1 mRNA]; Diazoxide inhibits the reaction [Oxygen deficiency results in decreased expression of HMOX1 mRNA]; Diazoxide inhibits the reaction [Oxygen deficiency results in decreased expression of HMOX1 protein]; Genistein inhibits the reaction [Oxygen deficiency results in increased expression of HMOX1 mRNA]; GSK3235025 inhibits the reaction [Oxygen deficiency results in decreased expression of HMOX1 protein]; HMOX1 mutant form inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [[Oxygen deficiency co-treated with IL1B protein] results in increased expression of TNF protein]]; HMOX1 mutant form inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [IL1B protein inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]]]; HMOX1 mutant form inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [IL1B protein inhibits the reaction [Oxygen deficiency results in increased expression of SOX9 protein]]]; HMOX1 mutant form inhibits the reaction [cobaltiprotoporphyrin promotes the reaction [IL1B protein inhibits the reaction [Oxygen deficiency results in increased expression of COL2A1 protein]]]; HMOX1 protein affects the reaction [Diazoxide inhibits the reaction [Oxygen deficiency results in increased expression of FLT1 protein]]; Oxygen deficiency inhibits the reaction [sodium arsenite results in increased expression of HMOX1 protein]; Particulate Matter promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 protein]; Plant Extracts inhibits the reaction [Oxygen deficiency results in increased expression of HMOX1 mRNA]; POR protein inhibits the reaction [Oxygen deficiency affects the localization of HMOX1 protein]; Resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of HMOX1 mRNA]; Vehicle Emissions promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 protein]
[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 mRNA; [Oxygen deficiency co-treated with Oxygen] results in increased expression of HMOX1 mRNA; HIPK2 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of HMOX1 mRNA]; HMOX1 protein promotes the reaction [Oxygen deficiency results in increased expression of CXCL12 mRNA]; HMOX1 protein promotes the reaction [Oxygen deficiency results in increased expression of CXCL12 protein]; HMOX1 protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; HMOX1 protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; MIR144 mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 mRNA]; PHLPP2 protein inhibits the reaction [Oxygen deficiency results in increased expression of HMOX1 mRNA]
[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of HMOX1 mRNA; [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with zinc protoporphyrin] results in increased expression of HMOX1 mRNA; [[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of HMOX1 mRNA; [[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of HMOX1 protein; [Antagomirs results in decreased expression of MIR30C1 mRNA] inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of HMOX1 protein]; [Antagomirs results in decreased expression of MIR30C1 mRNA] inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of HMOX1 protein]; [Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of HMOX1 mRNA; [Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of HMOX1 protein; [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of HMOX1 mRNA; [Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of HMOX1 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of HMOX1 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 protein; [Oxygen deficiency co-treated with Oxygen] results in increased expression of HMOX1 protein; cobaltiprotoporphyrin promotes the reaction [Oxygen deficiency results in increased expression of HMOX1 protein]; cobaltous chloride inhibits the reaction [Oxygen deficiency results in increased expression of HMOX1 mRNA]; cobaltous chloride promotes the reaction [Oxygen deficiency results in increased expression of HMOX1 protein]; diosmetin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of HMOX1 protein]; diosmetin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 mRNA]; diosmetin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 protein]; Ethanol inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of HMOX1 mRNA]; Ethanol inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of HMOX1 protein]; GSK3B protein inhibits the reaction [MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of HMOX1 mRNA]]; Hemin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of HMOX1 mRNA]; Hemin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of HMOX1 protein]; HMOX1 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of HMOX1 mRNA]; MIR30C1 mRNA promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of HMOX1 protein]; MIR30C1 mRNA promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of HMOX1 protein]; naringin promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of HMOX1 protein]; Oxygen deficiency results in increased expression of and results in increased activity of HMOX1 protein; PHLDA3 protein inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of HMOX1 protein]; PHLDA3 protein inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of HMOX1 protein]; saxagliptin promotes the reaction [Oxygen deficiency results in increased expression of HMOX1 mRNA]; saxagliptin promotes the reaction [Oxygen deficiency results in increased expression of HMOX1 protein]; Tea inhibits the reaction [Oxygen deficiency results in decreased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of HMOX1 protein]
