GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Srebf1 | decreases expression | ISO | SREBF1 (Homo sapiens) | 6480464 | CTD | Oxygen deficiency results in decreased expression of SREBF1 protein | PMID:24503013 | Srebf1 | increases expression | ISO | SREBF1 (Homo sapiens) | 6480464 | CTD | Oxygen deficiency results in increased expression of SREBF1 mRNA; Oxygen deficiency results in increased expression of SREBF1 protein | PMID:34648812 | Srebf1 | multiple interactions | ISO | SREBF1 (Homo sapiens) | 6480464 | CTD | [FV-429 compound co-treated with Oxygen deficiency] affects the expression of SREBF1 protein; [FV-429 compound co-treated with Paclitaxel] inhibits the reaction [Oxygen deficiency results in increased expression of SREBF1 protein]; [Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] promotes the reaction [Oxygen deficiency results in increased expression of SREBF1 protein]; [Paclitaxel co-treated with FV-429 compound] inhibits the reaction [Oxygen deficiency results in increased expression of SREBF1 mRNA]; [Paclitaxel co-treated with FV-429 compound] inhibits the reaction [Oxygen deficiency results in increased expression of SREBF1 protein]; EPAS1 gene mutant form inhibits the reaction [Oxygen deficiency results in decreased expression of SREBF1 protein]; HIF1A gene mutant form inhibits the reaction [Oxygen deficiency results in decreased expression of SREBF1 protein]; HIF1A protein affects the reaction [Oxygen deficiency results in increased expression of SREBF1 protein] | PMID:24503013 PMID:34648812 | | ||||||||||||||||||||||
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