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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62373
Species: Mus musculus
RGD Object: Gene
Symbol: Hes1
Name: hes family bHLH transcription factor 1
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hes1increases expressionEXP 6480464CTDOxygen deficiency results in increased expression of HES1 mRNA; Oxygen deficiency results in increased expression of HES1 proteinPMID:24223152
Hes1multiple interactionsEXP 6480464CTDN-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [Oxygen deficiency results in increased expression of HES1 protein]PMID:24223152
Hes1increases expressionISOHES1 (Homo sapiens)6480464CTDOxygen deficiency results in increased expression of HES1 mRNAPMID:26516004
Hes1increases expressionISOHes1 (Rattus norvegicus)6480464CTDOxygen deficiency results in increased expression of HES1 mRNAPMID:24223152
Hes1multiple interactionsISOHes1 (Rattus norvegicus)6480464CTDN-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [Oxygen deficiency results in increased expression of HES1 mRNA]PMID:24223152
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