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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620893
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prkaa2
Name: protein kinase AMP-activated catalytic subunit alpha 2
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prkaa2increases expressionEXP 6480464CTDOxygen results in increased expression of PRKAA2 mRNAPMID:22911455
Prkaa2multiple interactionsEXP 6480464CTDOxygen deficiency results in decreased expression of [PRKAA1 protein binds to PRKAA2 protein]; PRKAA2 mutant form inhibits the reaction [[Nitrites co-treated with Oxygen deficiency] results in increased expression of PPARGC1A mRNA]; sanggenone C inhibits the reaction [Oxygen deficiency results in decreased expression of [PRKAA1 protein binds to PRKAA2 protein]]PMID:22892143 PMID:28983604
Prkaa2increases expressionISOPRKAA2 (Homo sapiens)6480464CTDOxygen deficiency results in increased expression of PRKAA2 mRNAPMID:24236059
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