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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620795
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Src
Name: SRC proto-oncogene, non-receptor tyrosine kinase
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srcincreases phosphorylationEXP 6480464CTDOxygen deficiency results in increased phosphorylation of SRC proteinPMID:15913578
Srcmultiple interactionsEXP 6480464CTD[Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of SRC protein; Antigen-Antibody Complex inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of SRC protein]; Chlorpromazine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of SRC protein]PMID:29702141
Srcmultiple interactionsISOSRC (Homo sapiens)6480464CTD[Oxygen deficiency co-treated with Dasatinib] results in decreased phosphorylation of SRC protein; AG 1879 inhibits the reaction [Oxygen deficiency results in increased phosphorylation of and results in increased activity of SRC protein]; Oxygen deficiency results in increased phosphorylation of and results in increased activity of SRC proteinPMID:17671207 PMID:34717917
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