GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ptgs2 | affects expression | EXP | | 6480464 | CTD | Oxygen deficiency affects the expression of PTGS2 mRNA | PMID:17963755 | Ptgs2 | increases expression | EXP | | 6480464 | CTD | Oxygen deficiency results in increased expression of PTGS2 mRNA | PMID:21615343 | Ptgs2 | multiple interactions | EXP | | 6480464 | CTD | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of PTGS2 mRNA; [Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of PTGS2 mRNA; [Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of PTGS2 protein; Metoprolol inhibits the reaction [Oxygen deficiency results in increased expression of PTGS2 mRNA] | PMID:11567657 PMID:21615343 PMID:33729688 | Ptgs2 | increases expression | ISO | PTGS2 (Homo sapiens) | 6480464 | CTD | Oxygen deficiency results in increased expression of PTGS2 mRNA | PMID:20042640 PMID:35883890 | Ptgs2 | multiple interactions | ISO | PTGS2 (Homo sapiens) | 6480464 | CTD | [Oxygen deficiency co-treated with Catechin] results in increased expression of PTGS2 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] inhibits the reaction [Vehicle Emissions results in increased expression of PTGS2 protein]; HIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of PTGS2 mRNA] | PMID:20042640 PMID:28400208 PMID:35883890 | Ptgs2 | multiple interactions | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of PTGS2 mRNA; [Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of PTGS2 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of PTGS2 protein; NFKB1 protein inhibits the reaction [SOD1 protein promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of PTGS2 protein]]; SOD1 protein promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of PTGS2 protein] | PMID:16395278 PMID:19640911 PMID:30529165 | | ||||||||||||||||||||||
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