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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619788
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trpc6
Name: transient receptor potential cation channel, subfamily C, member 6
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpc6increases expressionISOTRPC6 (Homo sapiens)6480464CTDOxygen deficiency results in increased expression of TRPC6 proteinPMID:30831131
Trpc6increases expressionISOTrpc6 (Mus musculus)6480464CTDOxygen deficiency results in increased expression of TRPC6 proteinPMID:30831131
Trpc6multiple interactionsISOTRPC6 (Homo sapiens)6480464CTDfasudil inhibits the reaction [Oxygen deficiency results in increased expression of TRPC6 protein]; HIF1A protein affects the reaction [Oxygen deficiency results in increased expression of TRPC6 protein]; Y 27632 inhibits the reaction [Oxygen deficiency results in increased expression of TRPC6 protein]PMID:30831131
Trpc6multiple interactionsISOTrpc6 (Mus musculus)6480464CTDfasudil inhibits the reaction [Oxygen deficiency results in increased expression of TRPC6 protein]; Y 27632 inhibits the reaction [Oxygen deficiency results in increased expression of TRPC6 protein]PMID:30831131
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