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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619783
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trpc1
Name: transient receptor potential cation channel, subfamily C, member 1
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpc1increases expressionEXP 6480464CTDOxygen deficiency results in increased expression of TRPC1 mRNA; Oxygen deficiency results in increased expression of TRPC1 proteinPMID:32956540
Trpc1multiple interactionsEXP 6480464CTDChloroquine inhibits the reaction [Oxygen deficiency results in increased expression of TRPC1 mRNA]; Chloroquine inhibits the reaction [Oxygen deficiency results in increased expression of TRPC1 protein]PMID:32956540
Trpc1increases expressionISOTRPC1 (Homo sapiens)6480464CTDOxygen deficiency results in increased expression of TRPC1 proteinPMID:30831131
Trpc1increases expressionISOTrpc1 (Mus musculus)6480464CTDOxygen deficiency results in increased expression of TRPC1 proteinPMID:30831131
Trpc1multiple interactionsISOTRPC1 (Homo sapiens)6480464CTDfasudil inhibits the reaction [Oxygen deficiency results in increased expression of TRPC1 protein]; HIF1A protein affects the reaction [Oxygen deficiency results in increased expression of TRPC1 protein]; Y 27632 inhibits the reaction [Oxygen deficiency results in increased expression of TRPC1 protein]PMID:30831131
Trpc1multiple interactionsISOTrpc1 (Mus musculus)6480464CTDfasudil inhibits the reaction [Oxygen deficiency results in increased expression of TRPC1 protein]; Y 27632 inhibits the reaction [Oxygen deficiency results in increased expression of TRPC1 protein]PMID:30831131
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