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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619755
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rac1
Name: Rac family small GTPase 1
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rac1multiple interactionsISORAC1 (Homo sapiens)6480464CTD[Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of RAC1 mRNA; [Oxygen co-treated with Ozone] results in decreased expression of RAC1 mRNA; APEX1 protein inhibits the reaction [RAC1 protein inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]]; RAC1 protein inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]; RAC1 protein inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 protein]PMID:12719791 PMID:32992648
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