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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2358
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ckm
Name: creatine kinase, M-type
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ckmmultiple interactionsEXP 6480464CTD[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased secretion of [CKM protein binds to CKB protein]; PHLDA3 protein promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased secretion of [CKM protein binds to CKB protein]]PMID:34351043
Ckmincreases expressionISOCKM (Homo sapiens)6480464CTDOxygen deficiency results in increased expression of CKM proteinPMID:22363556
Ckmmultiple interactionsISOCKM (Homo sapiens)6480464CTDOxygen inhibits the reaction [Oxygen deficiency results in increased expression of CKM protein]PMID:22363556
Ckmmultiple interactionsISOCkm (Mus musculus)6480464CTD[NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of CKM mRNAPMID:30529165
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