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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1604618
Species: Homo sapiens
RGD Object: Gene
Symbol: CYCS
Name: cytochrome c, somatic
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYCSaffects expressionEXP 6480464CTDOxygen deficiency affects the expression of CYCS proteinPMID:34900531
CYCSdecreases expressionEXP 6480464CTDOxygen deficiency results in decreased expression of CYCS mRNAPMID:26516004
CYCSmultiple interactionsEXP 6480464CTDbruceine D affects the reaction [Oxygen deficiency affects the expression of CYCS protein]PMID:34900531
CYCSincreases expressionISOCycs (Rattus norvegicus)6480464CTDOxygen deficiency results in increased expression of CYCS mRNA; Oxygen deficiency results in increased expression of CYCS proteinPMID:33413359
CYCSmultiple interactionsISOCycs (Rattus norvegicus)6480464CTD(2-isopropyl-5-methylcyclohexyl) diphenylphosphine oxide inhibits the reaction [[Apigenin co-treated with Oxygen deficiency] results in increased expression of CYCS protein]; [Apigenin co-treated with Oxygen deficiency] results in increased expression of CYCS protein; HIF1A protein inhibits the reaction [[Apigenin co-treated with Oxygen deficiency] results in increased expression of CYCS protein]; norwogonin inhibits the reaction [Oxygen deficiency results in increased expression of CYCS mRNA]; norwogonin inhibits the reaction [Oxygen deficiency results in increased expression of CYCS protein]; Rutin inhibits the reaction [Oxygen deficiency results in increased expression of CYCS mRNA]; Rutin inhibits the reaction [Oxygen deficiency results in increased expression of CYCS protein]PMID:31930969 PMID:33413359
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